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Tea is manufactured from the leaf and bud of Camellia sinensis . The majority of tea consumed worldwide is in the form of black tea, which is Class 2d (McGuffin et al. 1997). Green tea has been found in several mouse models to have anti-inflammatory and antitumorigenic properties. The polyphenolic constituent (–)-epigallocatechin-3-gallate is thought to be the active ingredient. Numerous studies of green tea and skin cancer were reviewed .

It was found that topical application or oral consumption of green tea protects against inflammation, chemical carcinogenesis, and photocarcinogenesis. Green tea demonstrated the blocking of many mediators in the inflammatory process important in the early steps of skin tumor promotion. It also appears that there is inhibition of biochemical markers of chemical carcinogenesis, inhibition of UV-induced oxidative stress, and prevention of UV-induced immunosuppression as a result of action of green tea. Green tea also protects against psoralen UV-A-induced photochemical damage to the skin (Zhao Jin and Yaping et al. 1999). Many cosmetics and skin care products have been recently supplemented with green tea, but more research in humans is needed to understand the true benefits. Black tea may also play a role in the prevention of skin tumors.

It appears that theaflavins are the components active in chemoprevention (Nomura et al. 2000). Oral administration of black tea was also found to inhibit tumor proliferation and promote tumor apoptosis in nonmalignant and malignant skin tumors (Lu et al. 1997). A survey of older patients compared tea consumption and history of squamous cell carcinoma.

There was a lower risk of squamous cell carcinoma in patients who regularly consumed hot black tea than in nonconsumers . Caffeinated teas seem to be more protective than decaffeinated teas, and caffeine by itself has some inhibitory effects on UV-B-induced carcinogenesis (Wang et al. 1994; Huang et al. 1997; Lou et al. 1999). Horse chestnut seed extract is one of the most researched herbal alternatives. Horse chestnut contains the plant compounds known as "terpenes," with the most active component being aescin . The mechanism of action appears to be related to the inhibition of leukocyte activation, an important pathophysiological mechanism contributing to CVI. Aescin is also thought to decrease vascular leakage by inhibiting elastase and hyaluronase, which are involved in proteoglycan degradation at the capillary endothelium .

Many double-blind, randomized trials of orally administered HCSE have been conducted on patients with CVI. It was demonstrated that HCSE decreases lower-leg volume as well as calf and ankle circumference. Patients also showed decreased symptoms such as fatigue, tenderness, and pruritus.

One study showed the relative equivalency of using HCSE compared with grade II compression stockings for treatment of CVI . Most of the studies achieved statistically significant results for treatment of CVI with doses of HCSE containing 100–150 mg of aescin per day, most often taken as 50 mg twice a day. Adverse effects reported were minimal and included gastrointestinal tract discomfort, dizziness, headache, and pruritus. Rates of reported adverse effects were from 0.9% to 3.0% and in several studies were not statistically different from rates of adverse effects observed with placebo. Although there are no long-term studies of orally administered HCSE in treating CVI and its sequelae, these results seem promising and offer patients a safe alternative to compression stockings. In Europe, HCSE has also been used in the form of a topical gel, lotion, or ointment to reduce inflammation and discomfort associated with varicose veins, phlebitis, and hemorrhoids .

We have both male and female rats ready for their new homes.Due to the many zoonotic viruses and bacteria most are found in wild speciesincluding the recent Seoul Hantavirus found in the Midwest pet rats Jan. Buyers please be aware that even though a breeder may have tested negative for a disease, these illnesses may be picked up after your purchase, especially if wild rodents have access to your pets or their food or bedding. Honey has been used topically for centuries to assist healing of wounds, including burns, decubitus ulcers, and infected wounds . It has been found in vitro to have antibacterial and antifungal activity against organisms that commonly infect surgical wounds . The wounds were then treated with 5–10 mL of fresh, unprocessed honey twice a day.

There was marked clinical improvement by day 5, and by day 21, the wounds were all closed, clean, and sterile (Vardi et al. 1998). In a randomized controlled trial, honey-impregnated gauze was compared with a polyurethane film (OpSite, manufactured by Smith & Nephew, North Humberside, England) for partial-thickness burns. There have been no reports of significant adverse effects, although there are reports of contact dermatitis to honey . One commonly used TCM, Radix Angelicae dahurica, included in Class 1 (McGuffin et al. 1997), contains the furocoumarins imperatorin, isoimperatorin, and alloimperatorin. In a study involving 300 patients with psoriasis, this TCM, taken orally, was combined with UV-A therapy and was compared with the standard treatment of psoralen—UV-A with methoxsalen.

The efficacy of the two treatments was equivalent; however, there were fewer adverse effects such as nausea and dizziness in the group treated with TCM and UV-A . In addition, there are topical preparations made from herbs that show systemic efficacy against psoriasis, but are too toxic when given systemically . Topical TCM of the plant Camptotheca acuminata in an open trial including 92 patients with psoriasis found that this TCM was statistically more effective than 1% hydrocortisone. A disadvantage was that allergic contact dermatitis was seen in 9–15% of the patients in the TCM group. Some types of TCM may act in part on the microcirculation of the psoriatic lesion . Additional TCM herbal mixtures for psoriasis are listed by Xu .

Jewelweed is alleged to be useful topically for treating poison ivy contact dermatitis, but research results are conflicting. In one study, treatment with jewelweed was found to be comparable with standard treatment for poison ivy contact dermatitis, and in 108 of 115 patients studied, the symptoms cleared within 2–3 days . However, in another study, jewelweed extract failed to decrease symptoms of poison ivy dermatitis . In yet another study, no prophylactic effect of jewelweed in treating poison ivy dermatitis was reported .

Jewelweed has been said to be most effective if applied to the area where the poison ivy touched as soon as possible after contact, but this aspect was not addressed by the aforementioned studies. There have been no reports of topical jewelweed causing adverse effects . The ingredients of the placebo included 50% ethanol, 48% water, and 2% odorizing and coloring agents consisting of cherry laurel water, cinnamon water, licorice syrup, sugar syrup, and a solution of burned sugar. In both groups, there was an increase in nonvellus hairs. Although the Dabao group was statistically superior to the placebo group in number of nonvellus hairs, the cosmetic improvement in both groups was minimal.

Other TCM herbal mixtures have also been used for alopecia areata . I have plenty of males and females Pets Small Furries Rats Hampshire. Various dumbo rat kittens ready for new homes now.

Essential oils have been studied in a randomized, controlled, double-blind study of 86 patients with alopecia areata . A mixture of essential oils including thyme, rosemary, lavender, and cedarwood in carrier oils with grape seed and jojoba was massaged into the scalp daily. The control group massaged only the carrier oils into the scalp. Success was evaluated on the basis of sequential photographs, by both a six-point scale and a computerized analysis of areas of alopecia. The treatment group had a statistically significant improvement over the control group (44% vs. 15%).

Tea tree oil is an essential oil extracted from the leaves of Melaleuca alternifolia, a small tree indigenous to Australia. It contains approximately 100 compounds, mainly plant terpenes and their corresponding alcohols . A study of 124 patients compared 5% tea tree oil in a water-based gel with 5% benzoyl peroxide.

There have been occasional reports of allergic contact dermatitis (de Groot and Weyland 1993; Knight and Hansen 1994; Selvaag, Eriksen, and Thure 1994) and of poisoning if taken internally (Elliot 1993; Moss 1994). However, it is the degradation products of monoterpenes in the tea tree oil that actually appear to be the sensitizing agents . Hence, topical treatment is considered very safe. There are many possible drug interactions with herbs and prescription medications. It is crucial for patients to share information about what herbs, supplements, and other over-the-counter remedies they are taking or applying to their skin with their physicians. Some herbs are reported to cause hepatic damage, and they should not be used in combination with medications such as methotrexate.

These include many of the ingredients in TCM preparations, as well as Echinacea, chaparral, germander, ragwort, and life root (Ferguson, Chalmers, and Rowlands 1997; Borins 1998). Herbs containing y-linolenic acid, such as evening primrose oil, which has been used for treating dermatitis, psoriasis, and xerosis, lower the seizure threshold; thus, dosages of anticonvulsants may need to be increased . Rue and other herbs containing psoralens can cause phototoxic reactions externally on the skin . In addition to making them aware of the adverse effects already discussed, patients should be counseled on the relative lack of regulation for herbal medicines. There are minimal quality-control requirements currently in place in the United States to ensure the purity, concentration, or safety of herbal supplements. Although herb manufacturers are restricted from making efficacy statements, there are no regulations on claims for what symptoms these herbs can alleviate.

In the United States, there are also minimal regulations on which herbs can be restricted in formulations . Serious systemic adverse effects have been reported with the use of TCM herbal mixtures for the treatment of dermatologic disorders. Although most patients recover without serious consequences as long as the medication is stopped, there have been reports of patients with acute liver failure leading even to death. There are also reports of renal failure and agranulocytosis (Graham-Brown 1992; Mostefa-Kara et al. 1992; Koo and Arain 1998).

One patient was described with adult respiratory distress syndrome after administration of a TCM, kamisyoyo-san, for seborrheic dermatitis (Shota et al. 1961). A patient was reported with reversible dilated cardiomyopathy after receiving treatment for her atopic dermatitis with a Chinese herbal tea . There are also reports of Chinese and Indian herbal medicines containing as contaminants heavy metals, such as lead, arsenic, and mercury. Prescription medications have also been found in over-the-counter herbal formulations from other countries. Some herbs are mislabeled or misidentified. Marigold has been used topically since ancient times and is approved by the German regulatory authority Commission E as an antiseptic and for wound healing .

A topical preparation of marigold continues to be recommended for the treatment of wounds, ulcers, burns, boils, rashes, chapped hands, herpes zoster, and varicose veins. Marigold gargles are used for mouth and throat inflammation . Marigold is also widely used as a topical treatment for diaper dermatitis and other mild skin inflammations .

The treatment consists of an application several times a day of an ointment or a cream made by mixing 2–5 g of the flower heads with 100 g of ointment. A gargle or lotion is made by mixing 1–2 tsp (5–10 mL) of tincture with 0.25–0.5 L of water . The main adverse event is allergic contact dermatitis. No serious adverse effects have been reported, and it is considered safe to use both topically and orally. The anti-inflammatory effects of marigold are ascribed to the presence of triterpenoids. In animal studies, Calendula was suggested to stimulate granulation and increase glycoproteins and collagen at wound sites .

Marigold also shows in vitro antimicrobial and immune-modulating properties . Capsaicin is the main ingredient in cayenne pepper (C. frutescens), which is Class 1 internally but Class 2d externally (McGuffin et al. 1997); it has also been studied for the treatment of psoriasis. In vitro, capsaicin was found to inhibit phorbol ester-induced activation of transcription factors NF-κB and AP-1 (Surh et al. 2000). Two trials showed that 0.025% cream used topically is effective in treating psoriasis.

The first study showed a significant decrease in scaling and erythema during a 6-week period in 44 patients with moderate and severe psoriasis (Bernstein et al. 1986). The main adverse effect reported was a brief burning sensation at the application site. Capsaicin is contraindicated on injured skin or near the eyes, and the German authority Commission E suggests it should not be used for more than 2 consecutive days, with a 14-day lapse between applications. A tea is made by using 2–3 teaspoons (tsp; 10–15 mL) of dried flowers per cup of water and is taken internally or used as a compress.

Topical preparations with cream or ointment bases are also used and researched in Germany . Studies have demonstrated that topical chamomile is comparable with 0.25% hydrocortisone and shows improvement in sodium lauryl sulfate–induced contact dermatitis . A small double-blind trial found that chamomile significantly decreased the surface area of wounds and, in animal studies, healing time was found to be reduced with chamomile. Chamomile also shows in vitro antimicrobial activities . The main adverse effect reported is allergic contact dermatitis.

Chamomile is considered safe to use topically and orally, and is included in Class 1 (McGuffin et al. 1997). The anti-inflammatory, wound-healing, and antimicrobial effects of German chamomile are attributed to an essential blue oil that contains sesquiterpene alcohol, α-bisabolol, chamazulene, and flavinoids. These substances showed anti-inflammatory and antispasmodic properties in animal studies, due in part to the inhibition of cyclooxygenase and lipoxygenase in vitro. The flavinoids also act by inhibiting histamine release from antigen-stimulated human basophilic polymorphonuclear leukocytes . The substance α-isabolol also demonstrated promotion of granulation tissue in wound healing . Bittersweet nightshade (S. dulcamara) and brewer's yeast (S. cerevisiae) are thought to have similar anti-inflammatory and antibacterial effects.

Lovely friendly baby rats ready for new home!! Rex Hairless, albinos and dumbo rats available. All baby rats are having anti parasite treatment. You're more than welcome to negotiate the price. Herbal therapies vary greatly in their safety class ratings.

For example, some are consumed as foods and have high safety ratings, whereas others are highly biologically active and toxic and must be used very carefully. Many cutaneous reactions to herbal preparations have been reported, with the most common cutaneous adverse event being allergic contact dermatitis. More serious cutaneous reactions have been reported.

Bullous and nodular lichen planus were reported to be induced by ingestion of native African herbal medicines . A young woman was also described with leukemia-related Sweet syndrome elicited by a pathergic response to topical arnica cream (Delmonte et al. 1998). Aloe vera , which is Class 1 internally and Class 2d externally (McGuffin et al. 1997), has been used for centuries in wound healing and was recently found to be a potential treatment for psoriasis.

In a double-blind placebo-controlled study, 60 patients with slight to moderate plaque psoriasis were treated topically with either 0.5% hydrophilic aloe cream or placebo. The aloetreated group showed statistically significant improvement (83.3%) compared with the placebo group (6.6%). There were no adverse effects reported in the treatment group (Syed et al. 1996). Lemon balm is a lemon-scented member of the mint family.

An essential oil can be steam-distilled from the cut leaves. Topical uses include treatment of herpes simplex and minor wounds. In a randomized, double-blind trial of 116 patients with herpes simplex lesions, 96% reported complete clearing of lesions at day 8 after using 1% balm extract cream five times a day . In another trial where balm extract was placed on lesions within 72 hours of the onset of symptoms, the size of the lesions and healing time were found to be statistically better in the group treated with balm . Tannin and polyphenols appear to be responsible for the antiviral effect of the balm .

Balm is included in Class 1, and is very safe to use both topically and orally (McGuffin et al. 1997; Peirce, Fargis, and Scordato 1999). Arnica is derived from the dried flowers of Arnica montana or other arnica species. Although oral administration can cause severe health hazards even in small amounts, preparations for external use are very safe and effective.